A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate

Ram S. Mohan; Matthew R. Bockman; Veronica V. Angeles; Julia M. Martino; Purav P. Vagadia

A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate

Ram S. Mohan
, Matthew R. Bockman
, Veronica V. Angeles
, Julia M. Martino
, Purav P. Vagadia

Illinois Wesleyan University

Research output: Journal Article › Article › peer-review

Abstract

A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

Original language	American English
Journal	Tetrahedron Letters
Volume	52
State	Published - 2011

Disciplines

Organic Chemistry

Cite this

@article{1128d78b2ceb4b4baec858d127a545f0,

title = "A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate",

abstract = " A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol \%) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.",

author = "Mohan, \{Ram S.\} and Bockman, \{Matthew R.\} and Angeles, \{Veronica V.\} and Martino, \{Julia M.\} and Vagadia, \{Purav P.\}",

year = "2011",

language = "American English",

volume = "52",

journal = "Tetrahedron Letters",

}

TY - JOUR

T1 - A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate

AU - Mohan, Ram S.

AU - Bockman, Matthew R.

AU - Angeles, Veronica V.

AU - Martino, Julia M.

AU - Vagadia, Purav P.

PY - 2011

Y1 - 2011

N2 - A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

AB - A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

M3 - Article

VL - 52

JO - Tetrahedron Letters

JF - Tetrahedron Letters

ER -