A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate

Ram S. Mohan; Matthew R. Bockman; Veronica V. Angeles; Julia M. Martino; Purav P. Vagadia

A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate

Ram S. Mohan, Matthew R. Bockman, Veronica V. Angeles, Julia M. Martino, Purav P. Vagadia

Illinois Wesleyan University

Research output: Journal Article › Article › peer-review

Abstract

A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

Original language	American English
Journal	Tetrahedron Letters
Volume	52
State	Published - 2011

Disciplines

Organic Chemistry

Cite this

@article{1128d78b2ceb4b4baec858d127a545f0,

title = "A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate",

abstract = " A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol \%) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.",

author = "Mohan, \{Ram S.\} and Bockman, \{Matthew R.\} and Angeles, \{Veronica V.\} and Martino, \{Julia M.\} and Vagadia, \{Purav P.\}",

year = "2011",

language = "American English",

volume = "52",

journal = "Tetrahedron Letters",

}

TY - JOUR

T1 - A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate

AU - Mohan, Ram S.

AU - Bockman, Matthew R.

AU - Angeles, Veronica V.

AU - Martino, Julia M.

AU - Vagadia, Purav P.

PY - 2011

Y1 - 2011

N2 - A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

AB - A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

M3 - Article

VL - 52

JO - Tetrahedron Letters

JF - Tetrahedron Letters

ER -