The Discovery-Oriented Approach to Organic Chemistry. 5. Stereochemistry of E2 Elimination: Elimination of cis- and trans-2-Methylcyclohexyl Tosylate

Ram S. Mohan, Marcus E. Cabay, Brad J. Ettlie, Adam J. Tuite, Kurt A. Welday

Research output: Journal ArticleArticlepeer-review

Abstract

The E2 elimination is one of the most important reactions in organic chemistry and is discussed in considerable detail in a sophomore organic course. We have developed a discovery-oriented lab that illustrates the stereochemistry of the E2 elimination reaction and is a good exercise in 1H NMR spectroscopy. The added element of discovery insures that student interest and enthusiasm are retained.
Original languageAmerican English
JournalJournal of Chemical Education
Volume78
StatePublished - Jan 2001

Keywords

  • Second-year undergraduate
  • organic chemistry
  • inquiry-based discovery learning
  • IR spectroscopy.

Disciplines

  • Organic Chemistry

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